Cradle

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Healthcare

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Design better proteins

Cradle helps biologists design improved proteins in record time using powerful prediction algorithms and AI design suggestions.

// Overview

Save days of work.
Visualize, analyze, and predict candidates’ potential all in one place. In other words, know what works out in the real world – faster.

Improve with every round.
Train the Cradle AI with results from your wet lab to build a tailored model that improves candidates with each round of testing.

Low throughput, big results
Use Cradle for any project. No high throughput assay? No problem. Get impressive results between rounds with just a 96 well plate.

Unlimited candidates
Choose what to improve, then generate quality candidates in just one click. Not feeling the results? Click again.

AI-assisted design tools

Predict a protein’s 3D structure, generate new sequences with improved thermostability, optimize codons and much more soon…

3D structure prediction
Predict the structure of an individual sequence or multimer with AlphaFold 2. Optimized for speed without compromising on accuracy.

Thermostability
Optimize the thermostability of your proteins with models trained on large datasets. Get even better suggestions after a round of experiments in the lab.

Codon optimization
Optimize your protein’s codons for better expression. Go beyond codon usage tables and leverage machine learning models that have seen DNA-Protein-sequence-pairs from your host.

Stability Design proteins that do better in harsher environments by improving their stability in solvents.

Activity Want your enzyme to go faster? Improve the rate by which your enzyme performs its reactions.

Specificity Design proteins that fit like a glove by optimizing their specificity.

Affinity Improve your protein’s affinity to increase protein-protein interactions.

Multiobjective Optimize all of the above by setting targets for multiple phenotypes simultaneously and let the models find an optimum.

Private. Secure. Yours.

Cradle keeps your sequences and data private and secure while giving you full ownership of all intellectual property.

Private by design
We think your sequences are incredibly valuable, but we’ll never know. Why? Only you and people you invite from your organization can access sequence data.

Safe & secure
As industry veterans, we know it all comes down to security. Cradle uses bank-grade level of security to keep your data safe.

Own your IP
We keep IP a lot simpler than we do security. How simple? It’s yours, you own the IP. How about royalties? Nope. You only pay for users and usage of our tools.

Cells – the factories of the future.
We believe cells can theoretically produce almost anything, from fabrics to food, fuel and medicines. Designing cell-factories is hard, but our tools and machine learning models can make it easier. Our mission is to ultimately help replace traditional farms and factories for a more sustainable world.

Backed by the best

We are funded by leading investors Index Ventures and Kindred Capital, as well as long list of world-class advisors and angel investors.

Index Ventures
Index helps entrepreneurs turn bold ideas into businesses that have a long-lasting positive impact on the world.

“We love Cradle because it is enabling a new wave of progress that aims to improve the health of both humanity and the planet.”

Kindred Capital
Kindred is an early investor in LabGenius, Ori, Eleven Tx, and others.

“We believe the next $100Bn opportunity will be built at the intersection of biology and computation, and that Europe can play a leading role on the global stage.”

Get early access

Want to be one of the first to design proteins using AI?

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